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The citric acid cycle | Cellular respiration (article) | Khan Academy

    https://www.khanacademy.org/science/biology/cellular-respiration-and-fermentation/pyruvate-oxidation-and-the-citric-acid-cycle/a/the-citric-acid-cycle
    Step 1. In the first step of the citric acid cycle, acetyl joins with a four-carbon molecule, oxaloacetate, releasing the group and forming a six-carbon molecule called citrate. Step 2. In the second step, citrate is converted into its isomer, isocitrate.

Citric Acid Cycle | Pathway - PubChem

    https://pubchem.ncbi.nlm.nih.gov/pathway/PathBank:SMP0063477
    The citric acid cycle begins with acetyl-CoA transferring its two-carbon acetyl group to the four-carbon acceptor compound (oxaloacetate) to form a six-carbon compound (citrate) through the enzyme citrate synthase. The resulting citrate is then converted to cis-aconitate and then isocitrate via the enzyme aconitase.

Biochemistry, Citric Acid Cycle - StatPearls - NCBI Bookshelf

    https://www.ncbi.nlm.nih.gov/books/NBK541072/
    The citric acid cycle serves as the mitochondrial hub for the final steps in carbon skeleton oxidative catabolism for carbohydrates, amino acids, and fatty acids. Each oxidative step, in turn, reduces a coenzyme such as nicotinamide adenine dinucleotide (NADH) or flavin adenine dinucleotide (FADH2). These reduced coenzymes contribute directly to the electron …

Citric Acid Cycle - HHMI BioInteractive

    https://www.biointeractive.org/classroom-resources/citric-acid-cycle
    The citric acid cycle is a key component of cellular respiration. The citric acid cycle gains two carbon atoms from glycolysis (first animation), and those atoms are split off one by one to be released as carbon dioxide. The reactions release chemical energy, which is captured as energy-rich reduced forms of cofactors.

7.3C: Citric Acid Cycle - Biology LibreTexts

    https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Book%3A_General_Biology_(Boundless)/07%3A_Cellular_Respiration/7.3%3A_Oxidation_of_Pyruvate_and_the_Citric_Acid_Cycle/7.3C%3A_Citric_Acid_Cycle
    Note that the citric acid cycle produces very little ATP directly and does not directly consume oxygen. Figure 7.3 C. 1: The citric acid cycle: In the citric acid cycle, the acetyl group from acetyl CoA is attached to a four-carbon oxaloacetate molecule to form a six-carbon citrate molecule. Through a series of steps, citrate is oxidized ...

Citric acid cycle - Wikipedia

    https://en.wikipedia.org/wiki/Citric_acid_cycle
    The citric acid cycle is a key metabolic pathway that connects carbohydrate, fat, and protein metabolism.The reactions of the cycle are carried out by eight enzymes that completely oxidize acetate (a two carbon molecule), in the form of acetyl-CoA, into two molecules each of carbon dioxide and water. Through catabolism of sugars, fats, and proteins, the two-carbon organic …

Krebs Cycle or Citric Acid Cycle: Steps, Products, Significance

    https://byjus.com/neet/krebs-cycle/
    Each citric acid cycle forms the following products: 2 molecules of CO 2 are released. Removal of CO 2 or decarboxylation of citric acid takes place at two places: In the conversion of isocitrate (6C) to 𝝰-ketoglutarate (5C) In the conversion of 𝝰-ketoglutarate (5C) to succinyl CoA (4C) 1 ATP is produced in the conversion of succinyl CoA to succinate

Carbon flux through citric acid cycle pathways in perfused heart …

    https://pubmed.ncbi.nlm.nih.gov/2879743/
    Hearts perfused with [2-13C]acetate show low but significant activity of the anaplerotic pathways. Activation of two different anaplerotic pathways is demonstrated by addition of unlabeled propionate or pyruvate to hearts perfused with [2-13C]acetate. In each case, the amount of [2-13C]acetate being oxidized and the relative carbon flux through ...

Lecture 4 - Citric Acid Cycle

    https://www.chem.uwec.edu/Chem454_S03/Pages/Overheads/C454_lect4_print.pdf
    The citric acid cycle oxidizes two carbon units. These enter the cycle as Acetyl-CoA Acetyl-CoA is synthesized from pyruvate or from fats 1. Oxidation of Two-Carbon Units 10 11 Acetyl-CoA is formed from pyruvate by an oxidative decarboxylation. 1.1. Formation of Acetyl-CoA Pyruvate C+CoA-SH+NAD+ O O O CH3 Acetyl-CoA C O C H3SCoA +OCONAD

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