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Eric M. Morrow Author Manuscript NIH Public Access Seung-Yun Y…
https://flavell.mit.edu/wp-content/uploads/2016/02/Identifying-autism-loci-and-genes-by-tracing-recent-shared-ancestry.pdf#:~:text=Although%20segregation%20analyses%20have%20supported%20a%20role%20for,of%20pedigrees%20with%20autism%20and%20recent%20shared%20ancestry
Identifying Autism Loci and Genes by Tracing Recent …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586171/
An increased role for inherited factors in autism families with shared ancestry was also suggested by a low rate of de novo CNVs that segregated with disease, despite the use of two sensitive methods for detecting them: the Affymetrix Gene-Chip Human Mapping 500K single-nucleotide polymorphism (SNP) array, as well as bacterial artificial chromosome (BAC) …
Identifying autism loci and genes by tracing recent …
https://pubmed.ncbi.nlm.nih.gov/18621663/
Abstract. To find inherited causes of autism-spectrum disorders, we studied families in which parents share ancestors, enhancing the role of inherited factors. We mapped several loci, some containing large, inherited, homozygous deletions that are likely mutations. The largest deletions implicated genes, including PCDH10 (protocadherin 10) and DIA1 (deleted in autism1, or …
Identifying Autism Loci and Genes by Tracing Recent Shared …
https://www.science.org/doi/10.1126/science.1157657
Abstract. To find inherited causes of autism-spectrum disorders, we studied families in which parents share ancestors, enhancing the role of inherited factors. We mapped several loci, some containing large, inherited, homozygous deletions that are likely mutations. The largest deletions implicated genes, including PCDH10 ( protocadherin 10) and ...
Identifying Autism Loci and Genes by Tracing Recent …
https://www.jstor.org/stable/20054472
be useful for identifying loci and genes in ASDs in consanguineous populations. Ascertainment of pedigrees with autism and recent shared ancestry. The Homozygosity Map ping Collaborative for Autism (HMCA) (21) has recruited 104 families (79 simplex and 25 multiplex) from the Arabic Middle East, Turkey, and Pakistan (table SI and fig. SI), of which 88
Identifying Autism Loci and Genes by Tracing Recent …
https://www.researchgate.net/publication/5230177_Identifying_Autism_Loci_and_Genes_by_Tracing_Recent_Shared_Ancestry
To find inherited causes of autism-spectrum disorders, we studied families in which parents share ancestors, enhancing the role of inherited factors. We mapped several loci, some containing large,...
Identifying Autism Loci and Genes by Tracing Recent Shared …
https://web.math.princeton.edu/~sswang/autism/morrow_walsh08_science_autism-loci-genes-ancestry.pdf
To find inherited causes of autism-spectrum disorders, we studied families in which parents share ancestors, enhancing the role of inherited factors. We mapped several loci, some containing large, inherited, homozygous deletions that …
Eric M. Morrow Author Manuscript NIH Public Access Seung …
https://flavell.mit.edu/wp-content/uploads/2016/02/Identifying-autism-loci-and-genes-by-tracing-recent-shared-ancestry.pdf
homozygosity mapping can be useful for identifying loci and genes in ASDs in consanguineous populations. Ascertainment of pedigrees with autism and recent shared ancestry The Homozygosity Mapping Collaborative for Autism (HMCA) ( 21) has recruited 104 families (79 simplex and 25 multiplex) from the Arabic Middle East, Turkey, and Pakistan (table S1
Identifying Autism Loci and Genes by Tracing Recent Shared …
http://walshlab.org/uploads/publications/19/identifying_autism_loci_and_genes_by_tracing_recent_shared_ancestry.pdf
Recent Shared Ancestry Identifying Autism Loci and Genes by Tracing www.sciencemag.org (this information is current as of December 8, 2008 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/321/5886/218 version of this …
Identifying Autism Loci and Genes by Tracing Recent Shared …
https://ui.adsabs.harvard.edu/abs/2008Sci...321..218M/abstract
To find inherited causes of autism-spectrum disorders, we studied families in which parents share ancestors, enhancing the role of inherited factors. We mapped several loci, some containing large, inherited, homozygous deletions that are likely mutations.
Linkage and candidate gene studies of autism spectrum …
https://www.ncbi.nlm.nih.gov/sites/ppmc/articles/PMC2987412/
Over the past decade, research on the genetic variants underlying susceptibility to autism and autism spectrum disorders (ASDs) has focused on linkage and candidate gene studies. This research has implicated various chromosomal loci and genes.
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