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The Theory and Practice of Lineage Tracing - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618107/
Lineage tracing - PubMed
https://pubmed.ncbi.nlm.nih.gov/22265400/
Lineage tracing is the identification of all progeny of a single cell. Although its origins date back to developmental biology of invertebrates in the 19 (th) century, lineage tracing is now an essential tool for studying stem cell properties in adult mammalian tissues. Lineage tracing provides a powerful means of understanding tissue development, homeostasis, and disease, …
Lineage tracing meets single-cell omics: opportunities …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307462/
A lineage-tracing experiment that involves marking an individual cell, followed by state analysis of that founder cell’s clonal descendants. Retrospective lineage tracing A lineage-tracing experiment based on phylogenetic reconstruction of endogenous genetic polymorphisms (that is, no experimental intervention).
Methods in lineage tracing - ScienceDirect
https://www.sciencedirect.com/science/article/pii/B9780128148419000816
Chapter 81 - Methods in lineage tracing Introduction. Lineage tracing is an approach that has been widely used in developmental biology to identify the origin... Cre recombinase. Genetic manipulation has been utilized to direct the specific overexpression or deletion of genes. As... Reporters. ...
Lineage Tracing | Ivory Research
https://www.ivoryresearch.com/samples/lineage-tracing/
Classically, lineage tracing is divided into prospective analysis, mosaic analysis, and retrospective analysis. Each of these methods can be used independently or simultaneously with each other to map stem cell fates and determine cell lineage. Prospective Lineage Analysis
Lineage Tracing: Cell
https://www.cell.com/abstract/S0092-8674%2812%2900003-7
Lineage tracing is the identification of all progeny of a single cell. Although its origins date back to developmental biology of invertebrates in the 19 th century, lineage tracing is now an essential tool for studying stem cell properties in adult mammalian tissues. Lineage tracing provides a powerful means of understanding tissue development, homeostasis, and …
Lineage Tracing - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S0092867412000037
Lineage tracing is the identification of all progeny of a single cell. Although its origins date back to developmental biology of invertebrates in the 19 th century, lineage tracing is now an essential tool for studying stem cell properties in adult mammalian tissues. Lineage tracing provides a powerful means of understanding tissue development, homeostasis, and …
Lineage tracing: technology tool for exploring the …
https://stemcellres.biomedcentral.com/articles/10.1186/s13287-020-01941-y
Lineage tracing is the most widely used technique to track the migration, proliferation, and differentiation of specific cells in vivo. The currently available gene-targeting technologies have been developing for decades to study organogenesis, tissue injury repairing, and tumor progression by tracing the fates of individual cells.
Methods for analysing lineage tracing datasets - Royal …
https://royalsocietypublishing.org/doi/10.1098/rsos.202231
The ‘single-progenitor’ (SP) model (figure 1b) has been shown over several studies to accurately describe the observed progenitor cell dynamics in transgenic lineage tracing experiments [1–7]. Using three parameters, the division rate, the stratification rate and the probability of symmetric division, this model predicts average clone size, clone size …
Lineage tracing on transcriptional landscapes links state …
https://www.science.org/doi/10.1126/science.aaw3381
LARRY defines a scSeq-compatible lineage-tracing approach that links cell states to clonal fates simultaneously from multiple initial conditions without the need to target each specific progenitor state. The strategy differs from CRISPR-based lineage-tracing approaches (27, 28) in that it links states across time, not only at a single end point. LARRY is simple to use; …
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