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Lineage analysis of stem cells - StemBook - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK27073/
Lineage tracing - PubMed
https://pubmed.ncbi.nlm.nih.gov/22265400/
Lineage tracing is the identification of all progeny of a single cell. Although its origins date back to developmental biology of invertebrates in the 19 (th) century, lineage tracing is now an essential tool for studying stem cell properties in adult mammalian tissues. Lineage tracing provides a powerful means of understanding tissue development, homeostasis, and disease, …
Lineage analysis of stem cells | StemBook
https://www.stembook.org/node/542
The hematopoietic stem cell lineage tracing method of choice has therefore been transplantation. This technique was used to establish that the hematopoietic stem cell is capable of giving rise to both myeloid and lymphoid lineages using cells marked by radiation induced chromosomal changes (Abramson, 1979 ).
Stem cells: lineage tracing lets single cells talk about …
https://www.nature.com/articles/s41592-018-0016-0
Multipotent stem cells can become a variety of cell types. A flurry of new approaches enable lineage tracing at single-cell resolution.
Lineage tracing: technology tool for exploring the …
https://stemcellres.biomedcentral.com/articles/10.1186/s13287-020-01941-y
Since the pancreas, liver, and intestines originate from the embryonic endoderm, many studies have used lineage tracing to track specific markers of endoderm cells to continuously monitor the fates of stem cells in organs such as the pancreas [96,97,98,99]. As early as 2002, Kawaguchi et al. carried out lineage tracing of cells expressing Ptf1a, disproving …
Lineage Tracing Reveals a Subset of Reserve Muscle …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597014/
In the intestine, lineage tracing and label retention assays show that the intestine contains two populations of stem cells: a radiosensitive, rapidly dividing subset and a rarer, dormant (label-retaining) radiotolerant population, termed a reserve cell (Metcalfe et al., 2014; Montgomery et al., 2011; Tian et al., 2011). The reserve stem cell ...
Lineage Tracing: Cell Stem Cell
https://www.cell.com/i3/cell-stem-cell/lineage
Special Digital Issue: Cell Stem Cell 10-Year Anniversary. This month's cover highlights our tenth anniversary review feature inspired by the theme of “Lineage Tracing” and how new scientific discoveries build on those that came before. We've made this issue freely available as a digital issue. Download.
The Theory and Practice of Lineage Tracing - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618107/
Lineage tracing is a method that delineates all progeny produced by a single cell or a group of cells. The possibility of performing lineage tracing initiated the field of Developmental Biology, and continues to revolutionize Stem Cell Biology. Here, I introduce the principles behind a successful lineage-tracing experiment.
In Vivo Genetic Strategies for the Specific Lineage …
https://pubmed.ncbi.nlm.nih.gov/30047336/
Background: Characterization of the fate changes of stem cells is essential to understand the roles of certain stem cells both during development and in diseases, such as cancer. In the past two decades, more and more importance has been paid to the studies of in vivo lineage tracing, because they could authentically reveal the differentiation, migration and even proliferation of …
Lineage Analysis of Epidermal Stem Cells - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869281/
Lineage tracing has revealed normal cell behavior and produced startling insights into stem cell behavior. Rather than every stem cell behaving in the same manner, the maintenance of IFE and possibly the hair follicle depends on balancing the probabilities of differentiation and self-renewal over the stem/progenitor cell population.
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