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Lineage Tracing - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S0092867412000037
What do the lineage tracing studies tell us? Consideration …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450395/
Following to the report of VE-cad lineage tracing study above, Chen et al. further asked a question about a role of Runx1 expressed in the HEC[21]. First, they generated VE-cad Cre: R26R-YFP line to trace VE-cad+ cells and confirmed that VE-cad+ cells produced all blood cells in the E15 fetal liver and adult BM. Next, they deleted the
Lineage tracing: technology tool for exploring the …
https://stemcellres.biomedcentral.com/articles/10.1186/s13287-020-01941-y
Lineage tracing is the most widely used technique to track the migration, proliferation, and differentiation of specific cells in vivo. The currently available gene-targeting technologies have been developing for decades to study organogenesis, tissue injury repairing, and tumor progression by tracing the fates of individual cells.
Lineage tracking - Latest research and news | Nature
https://www.nature.com/subjects/lineage-tracking
Lineage tracking methods follow the position and behaviour of cells and their descendents over time. Cells are typically labelled and/or imaged in …
What do the lineage tracing studies tell us? Consideration …
https://pubmed.ncbi.nlm.nih.gov/30264284/
What do the lineage tracing studies tell us? Consideration for hematopoietic stem cell origin, dynamics, and leukemia-initiating cells The recent advance of technologies enables us to trace the cell fate in vivo by marking the cells that express the gene of interest or by barcoding them at a single cell level.
How Lineage Tracing Studies Can Unveil Tumor …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8772890/
Lineage tracing studies have become a well-suited approach to reveal cellular hierarchies and tumor heterogeneity. Cellular heterogeneity, particularly in breast cancer, is still one of the main concerns regarding tumor progression and resistance to anti-cancer therapies.
Methods in lineage tracing - ScienceDirect
https://www.sciencedirect.com/science/article/pii/B9780128148419000816
Lineage tracing is an approach that has been widely used in developmental biology to identify the origin and fate of cells. Lineage tracing studies have been performed in numerous organisms for over a century using various methods to identify and track cells (reviewed in Stern and Fraser, 2001 ).
Biomedicines | Free Full-Text | How Lineage Tracing …
https://www.mdpi.com/2227-9059/10/1/3/htm
Lineage tracing studies have become a well-suited approach to reveal cellular hierarchies and tumor heterogeneity. Cellular heterogeneity, particularly in breast cancer, is still one of the main concerns regarding tumor progression and resistance to anti-cancer therapies.
How Lineage Tracing Studies Can Unveil Tumor …
https://pubmed.ncbi.nlm.nih.gov/35052683/
Lineage tracing studies have become a well-suited approach to reveal cellular hierarchies and tumor heterogeneity. Cellular heterogeneity, particularly in breast cancer, is still one of the main concerns regarding tumor progression and resistance to anti-cancer therapies. Here, we review the current knowledge about lineage tracing analyses that ...
Scientists Develop New Method to Trace Cell Lineage
https://news.feinberg.northwestern.edu/2020/07/scientists-develop-new-method-to-trace-cell-lineage/
Previous studies using older methods of lineage tracing suggested that progenitor cells are not uniform and instead are heterogenous, with some progenitor cells marked by a transcription factor called Cux2+ that gave rise to the upper layers of neurons.
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