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Transneuronal Definition & Meaning | Merriam-Webster …
https://www.merriam-webster.com/medical/transneuronal
Medical Definition of transneuronal. : transsynaptic transneuronal cell atrophy.
Transneuronal Circuit Tracing with Neurotropic Viruses
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698966/
V. Tracing connections between specific cell types and controlling the extent of spread. Due to the complexity of the nervous system, it is extremely valuable to be able to trace connections to or from particular cell types.
Transneuronal Tracers | SpringerLink
https://link.springer.com/referenceworkentry/10.1007%2F978-3-540-29678-2_6091
Transneuronal tracers, such as barley lectin, are molecules that are transported through the axons and/ or dendrites of neurons and that can be transferred to other neurons at or near synapses. Transneuronal tracers can be visualized by histochemical techniques, thereby revealing the locations of connected neurons.
Viral Transneuronal Tracing Technology: Defining the …
https://onlinelibrary.wiley.com/doi/10.1002/9780470015902.a0022359
Viral transneuronal tracing is a powerful approach that has been widely used to define the cellular organisation of functionally defined systems that underlie brain function. The method exploits the ability of neurotropic viruses to infect neurons and produce infectious progeny that pass through the intimate synaptic connections among neurons to infect …
Transneuronal tracing to map connectivity in injured and …
https://www.sciencedirect.com/science/article/pii/S0014488622000152
TRANSNEURONAL TRACING: refers to anatomical tracers used to label multiple neurons interconnected within a network. Once the tracer is taken up by a neuron (first-order labeling), it replicates within the cell, moves to post-synaptic terminal, and crosses the synaptic junction to be taken up by neurons innervating the first-order-labeled neuron.
Tracing neuronal circuits in transgenic animals by …
https://pubmed.ncbi.nlm.nih.gov/29231171/
Tracing neuronal circuits in transgenic animals by transneuronal control of transcription ( TRACT) Understanding the computations that take place in brain circuits requires identifying how neurons in those circuits are connected to one another. We describe a technique called TRACT (<i>TRA</i>nsneuronal <i>C</i>ontrol of <i>T</i>ranscription) based on ligand-induced …
Advances in viral transneuronal tracing - ScienceDirect
https://www.sciencedirect.com/science/article/pii/S0165027009006232
Powerful transneuronal tracing technologies exploit the ability of some neurotropic viruses to travel across neuronal pathways and to function as self-amplifying markers. Two main classes of viral transneuronal tracers are available, derived from alpha-herpesviruses (Herpes Simplex virus type 1, Pseudorabies) and rabies virus.
Viruses as transneuronal tracers for defining neural circuits
https://pubmed.ncbi.nlm.nih.gov/9809303/
Abstract. Live viruses can be used as tools to label chains of neurons and thus to define functionally connected CNS circuits. This review summarizes the background and general principles involved in using the viral tracing technology. An attenuated form of a pig herpes virus, known as the Bartha's K strain of pseudorabies virus, has proven to ...
Viral neuronal tracing - Wikipedia
https://en.wikipedia.org/wiki/Viral_Neuronal_Tracing
Viral neuronal tracing is the use of a virus to trace neural pathways, providing a self-replicating tracer. Viruses have the advantage of self replication over molecular tracers, but can also spread too quickly and cause degradation of neural tissue. Viruses which can infect the nervous system, called neurotropic viruses, spread through spatially close assemblies of neurons through …
Retrograde tracing - Wikipedia
https://en.wikipedia.org/wiki/Retrograde_tracing
Retrograde tracing is a research method used in neuroscience to trace neural connections from their point of termination to their source. Retrograde tracing techniques allow for detailed assessment of neuronal connections between a target population of neurons and their inputs throughout the nervous system. These techniques allow the "mapping" of connections between …
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