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Zoom zoom: racing CARs for multiple myeloma - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630266/
In this issue of Clinical Cancer Research, Carpenter and colleagues 1 explore the potential of targeting the B cell maturation antigen (BCMA) with chimeric-antigen receptor (CAR)-transduced T cells, with the goal of developing a clinical T cell therapy to treat multiple myeloma. CAR-T cells are autologous or allogeneic T cells genetically ...
Zoom Zoom: racing CARs for multiple myeloma - PubMed
https://pubmed.ncbi.nlm.nih.gov/23444214/
Zoom Zoom: racing CARs for multiple myeloma Clin Cancer Res. 2013 Apr 15;19(8):1917-9. doi: 10.1158/1078-0432.CCR-13-0168. Epub 2013 Feb 26. Authors ... BCMA is a promising target for CAR-T cells in multiple myeloma. Publication types Comment MeSH terms Animals ...
Zoom zoom: racing CARs for multiple myeloma
https://www.ncbi.nlm.nih.gov/sites/ppmc/articles/PMC3630266/
Chimeric antigen receptors re-direct T cells to surface antigens. Discovery and validation of appropriate target antigens expands the possible indications for CAR-T cells. BCMA is expressed only on mature B cells and plasma cells and promotes their survival. ...
Zoom Zoom: Racing CARs for Multiple Myeloma | Clinical Cancer …
https://aacrjournals.org/clincancerres/article/19/8/1917/207429/Zoom-Zoom-Racing-CARs-for-Multiple-MyelomaCARs
Abstract. Chimeric antigen receptors redirect T cells to surface antigens. Discovery and validation of appropriate target antigens expand the possible indications for chimeric-antigen receptor (CAR)-T cells. B-cell maturation antigen (BCMA) is expressed only on mature B cells and plasma cells and promotes their survival. BCMA is a promising target for CAR-T cells in …
Zoom Zoom: Racing CARs for Multiple Myeloma
https://clincancerres.aacrjournals.org/content/clincanres/early/2013/04/03/1078-0432.CCR-13-0168.full.pdf
Zoom Zoom: Racing CARs for Multiple Myeloma Marcela V. Maus and Carl H. June Chimeric antigen receptors redirect T cells to surface antigens. Discovery and validation of appropriate ... plasma cells, and some multiple myeloma cells, binds to BAFF independently but requires CD138 to act as a coreceptor to bind APRIL (10). In human multiple mye-
Zoom Zoom: racing CARs for multiple myeloma
https://www.researchgate.net/publication/235741205_Zoom_Zoom_racing_CARs_for_multiple_myeloma
The cell-surface protein B cell maturation antigen (BCMA, CD269) has emerged as a promising target for CAR-T cell therapy for multiple myeloma. In order to create a novel BCMA CAR, we generated a ...
[PDF] Zoom Zoom: Racing CARs for Multiple Myeloma
https://www.semanticscholar.org/paper/Zoom-Zoom%3A-Racing-CARs-for-Multiple-Myeloma-Maus-June/2274fc19ea4325ea9c99760c513dfde7b6b2ade7
BCMA is a promising target for CAR-T cells in multiple myeloma. Clin Cancer Res; 19(8); 1917–9. ©2013 AACR. B-cell maturation antigen is a promising target for CAR-T cells in multiple myeloma and discovery and validation of appropriate target antigens expand the possible indications for chimeric-antigen receptor (CAR)-T cells.
Zoom Zoom: racing CARs for multiple myeloma | Read by QxMD
https://read.qxmd.com/read/23444214/zoom-zoom-racing-cars-for-multiple-myeloma
Zoom Zoom: racing CARs for multiple myeloma. Marcela V Maus, Carl H June. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 2013 April 15, 19 (8): 1917-9. 23444214. Chimeric antigen receptors redirect T cells to surface antigens. Discovery and validation of appropriate target antigens expand the ...
Zoom Zoom: Racing CARs for Multiple Myeloma - CORE
https://core.ac.uk/download/pdf/192477270.pdf
Zoom Zoom: Racing CARs for Multiple Myeloma Marcela V. Maus and Carl H. June Chimeric antigen receptors redirect T cells to surface antigens. Discovery and validation of appropriate ... multiple myeloma cells to form an essential survival loop. Eur J Haematol 2009;83:119–29. 11. O'ConnorBP,RamanVS,EricksonLD,CookWJ,WeaverLK,Ahonen
Zoom Zoom: Racing CARs for Multiple Myeloma - Peeref
https://www.peeref.com/works/8415940
Zoom Zoom: Racing CARs for Multiple Myeloma Authors. Keywords - Journal. CLINICAL CANCER RESEARCH Volume 19, Issue 8, Pages 1917-1919 Publisher. American Association for Cancer Research (AACR) Online. 2013-02-27 DOI. 10.1158/1078-0432.ccr-13-0168 ...
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